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Emergent BioSolutions Receives FDA Approval Extending Shelf Life Of BioThrax (Anthrax Vaccine Adsorbed) To 4 Years
Emergent BioSolutions Inc. (NYSE:EBS) announced that its flagship product, BioThrax® (Anthrax Vaccine Adsorbed), has been granted a shelf life extension from 3 to 4 years by the U.S. Food and Drug Administration (FDA). Based on this approval, Emergent has achieved a contract milestone warranting a payment of approximately $30 million for doses previously delivered to the Strategic National Stockpile (SNS) under the terms of the company"s existing BioThrax procurement contracts with the Department of Health and Human Services (HHS). This amount is expected to be recognized as revenue in the second quarter of 2009. In addition, FDA approval of 4-year expiry dating results in an immediate price increase for the future delivery of BioThrax doses under the current contract as well as under the follow-on multi-year contract, valued at $405 million, for the delivery of 14.5 million doses of BioThrax.
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Senate Finance Committee Holds Second Closed-Door Meeting On Health Care Reform; Details Of House Energy And Commerce Committee Overhaul Plan Leaked
The Senate Finance Committee and the House Energy and Commerce Committee on Thursday both worked on health care proposals aimed at overhauling the U.S. health care system, CQ Today reports. In its second of three closed-door meetings, the Finance Committee came to "early, broad agreement" on some issues but continued to disagree over a public option as part of a reform bill. Meanwhile, portions of an overhaul plan being developed by the Energy and Commerce Committee were leaked on Thursday, after Democrats on the committee held a closed-door session on the topic earlier this week (Armstrong, CQ Today, 5/14). Finance Committee
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A Bidirectional Relationship Between Chronic Stress And Sleep Problems shown by study

According to a research abstract that will be presented on Wednesday, June 10, at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies, people with chronic stress report shorter sleep duration, worse sleep quality, and more daytime functioning impairments. Conversely, daytime functioning impairments and shorter sleep duration demonstrated a predictive relationship with habitual stress complaints. Results indicate that poor sleep may be a potential cause of stress; individuals who report more fatigue and less total sleep are more likely to report more stress. According to principal investigator Eric Powell, PhD, director of research at the Research Center at Clayton Sleep Institute in St. Louis, Mo., factors that were the best predictors of high stress were daytime functioning and typical amount of sleep. "The simplest, and likely best advice for individuals with high stress and poor sleep is to look at some of the lifestyle choices they are making and ensuring sufficient sleep is at the core of those choices," said Powell. The study involved data from 544 patients at the Midwestern metropolitan sleep center who received diagnostic polysomnograms. Participants ranged in age from 18 to 79 years, were not shift workers, and had no prior sleep disorder diagnosis. Subjects completed a brief estimate of their state and trait stress, and sleepiness was assessed subjectively; individuals were divided into low and high-trait stress groups. Abstract Title: Does Habitual Stress Cause Sleep Problems and Daytime Functioning Impairments, or is Stress the Result of Poor Sleep? Presentation Date: Wednesday, June 10 Category: Behavior, Cognition & Dreams Abstract ID: 1268 Kelly Wagner American Academy of Sleep Medicine


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