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Model For New Generation Of Blood Vessels Challenged
In-growth and new generation of blood vessels, which must take place if a wound is to heal or a tumor is to grow, have been thought to occur through a branching and further growth of a vessel against a chemical gradient of growth factors. Now a research team at Uppsala University and its University Hospital has shown that mechanical forces are considerably more important than was previously thought. The findings, published today in the journal Nature Medicine, open up a new field for developing treatments.
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NEJM Perspective Pieces Examine Physician Involvement In Health Reform, Congressional Progress On Reform
"Achieving Health Care Reform -- How Physicians Can Help," New England Journal of Medicine: In a perspective piece, Elliott Fisher, a professor of medicine and of community and family medicine at Dartmouth Medical School and associate director for Population Health and Policy at the Dartmouth Institute for Health Policy and Clinical Practice; Donald Berwick, a professor at the Harvard University School of Public Health Department of Health Policy and Management and president and CEO of the Institute for Healthcare Improvement; and Karen Davis, president of the Commonwealth Fund, call on physicians to "lead the change our country needs" on health reform. They suggest several areas for physicians to become involved, saying that physicians should "first help to create a shared vision that could overcome doctrinal divides" and that they also must "recognize that achieving savings sufficient to cover the cost of expanded coverage need not impose a hardship on patients or providers." Finally, physicians also must help with a health reform deal that "all stakeholders can support," the authors say (Fisher et al., NEJM, 5/21).
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NIH Stem Cell Rules Seriously Flawed, Says Stanford Expert
Today the National Institutes of Health released their final guidelines detailing what types of human embryonic stem cell research will qualify for federal funding. Although the rules permit federal funding of research on embryonic stem cell lines produced from excess early embryos from in vitro fertilization clinics, they disallow federal support of two key techniques used to derive embryonic stem cells in animals: that of transferring the genetic material from one cell into an egg without a nucleus, and that of stimulating an unfertilized egg to divide.
Sexual Health

Abusive Relationships Increase Women's Risk Of HIV Infection

A new study of nearly 14,000 U.S. women reveals that those who are in physically abusive relationships are at higher risk for HIV infection. The study, which appears in the May/June issue of the journal General Hospital Psychiatry, shows that "intimate partner violence," which is physical or sexual assault of a spouse or partner, has become a significant public health concern around the world. While research on the problem has taken place in Africa and India, the new study is the first to look at the issue among a large number of women in the United States. Researchers led by Jitender Sareen, M.D., used data from the National Epidemiologic Survey on Alcohol and Related Conditions, which conducted interviews with women ages 20 and older during 2004 to 2005. They analyzed information from 13,928 women who reported being in a romantic relationship during the last 12 months. Researchers asked the women whether they had experienced physical or sexual violence from their partner during the last year, and whether they had received a diagnosis of HIV during the same time. The researchers found that 5.5 percent of the women in relationships reported abuse by their partners. The rate of HIV infection in the women was 0.17 percent. The results showed that women who experience violence from their partners were more than three times as likely to have HIV infection as women who do not. In addition, almost 12 percent of HIV infection among women was due to intimate partner violence. "These numbers are solely due to forced sex on women from their infected partners. It is a substantial percentage," said Sareen, an associate professor of psychiatry at the University of Manitoba in Canada. "This is a very large sample of people and, on methodology side, it"s a decent study, so people will need to pay attention to it," said Julia Heiman, director of The Kinsey Institute for Research in Sex, Gender, and Reproduction at Indiana University. "The relationship between the two is definitely known worldwide," Heiman said. "The partner violence issue, however, is an important one that often gets lost. The numbers that the researchers found should make people take notice that partner violence is definitely a risk factor for HIV." General Hospital Psychiatry is a peer-reviewed research journal published bimonthly by Elsevier Science. For information about the journal, contact Wayne Katon, M.D., at (206) 543-7177. Sareen J, Pagura J, Grant B. Is intimate partner violence associated with HIV infection among women in the United States? General Hosp Psychiatry, 31(3), 2009. Health Behavior News Service


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