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Postoperative PSA And PSA Velocity Identify Presence Of Prostate Cancer After Various Surgical Interventions For Benign Prostatic Hyperplasia
UroToday.com - Men undergoing surgical interventions for BPH are still at risk for subsequent development of prostate cancer (CaP) due to residual tissue. It is suggested that PSA decreases approximately 0.1-0.3ng/ml for every 1g of prostate tissue removed. In the online edition of Urology, Dr. Brian Helfand and associates determined the PSA values and PSAV in patients who had undergone TURP, holmium laser resection of the prostate (HoLRP), or open prostatectomy (OP) for treatment of BPH and compare these values in patients with histologic BPH only with the values in those with incidentally found CaP.
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International Research Team Seeks To Unravel Flatworm Regeneration
Planarian flatworms are only a few millimeters up to a few centimeters in length, live in freshwater and are the object of intense research, because they possess the extraordinary ability to regenerate lost tissue with the help of their stem cells (neoblasts) and even grow an entirely new worm out of minute amputated body parts. Now researchers from the Max DelbrÃøck Center in Berlin, Germany together with researchers in the US and Canada present the first comprehensive catalogue of small RNAs of planaria, elements that regulate gene expression. They also have identified small RNAs which may play a role in regeneration and stem cell function, Nikolaus Rajewsky from the MDC points out (PNAS, Early Edition)*.
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Calixa Therapeutics Announces Initiation Of Phase 2 Clinical Trial Of Its Antibiotic, CXA-101, In Patients With Complicated Urinary Tract Infections
Calixa Therapeutics Inc. today announced the initiation of a Phase 2 clinical trial of CXA-101 in patients with complicated urinary tract infections. CXA-101 is a new broad-spectrum, parenteral cephalosporin antibiotic with excellent in vitro and in vivo activity against Pseudomonas aeruginosa, including drug resistant isolates. Calixa is investigating CXA-101 as a potential treatment for serious bacterial infections in hospitalized patients.
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GMC Appoints Niall Dickson At Its New Chief Executive

The General Medical Council has announced that it has appointed The King"s Fund"s chief executive Niall Dickson as its new chief executive. Niall Dickson will remain at the Fund until the end of the year before formally starting in his new role in January 2010. Commenting on the appointment, The King"s Fund"s chair Sir Cyril Chantler said: "Niall has been a superb asset to the Fund over the past six years. Under his leadership the Fund has raised its profile and strengthened its expertise in shaping policy, transforming services and supporting leaders in the health service. He has brought tremendous passion and dynamism to the organisation and has helped to cement the Fund"s role as the foremost, independent commentator on health care in this country. "One of Niall"s most significant legacies will be the strengthening of the Fund"s health care improvement work, which combines expertise in research, policy analysis and leadership to work directly with clinicians and managers to help them drive up standards, deliver better value and bring about lasting improvements in key areas. We have become more than a think tank and that is largely due to Niall"s vision for creating an organisation that is more relevant to those working in health and social care. "Niall"s time at the Fund will also be remembered for high profile research that has had a direct impact on policy. In particular, the review of social care funding led by Sir Derek Wanless helped convince policymakers of the need for reforming the social care system and led directly to a Green Paper, while the review Niall commissioned into the safety of maternity services, and the subsequent work now being carried out by the Fund with maternity units, has and will continue to have a real impact on front-line services. "And he has also created a tremendous re for the health and social care community following the major refurbishment of both our building and online res. The Fund now has a range of facilities and information services that will be of great value to professionals for many years to come." Sir Cyril added: "Niall leaves behind a strong senior management team that will continue to drive through the Fund"s strategy while his successor is recruited. Niall will be with us until the end of the year and we will be seeking to appoint the right candidate to progress the work of the Fund. We very much look forward to working with Niall at the GMC and wish him every success in his new role." Niall"s Dickson"s biography is available here. The King"s Fund


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