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Poniard Pharmaceuticals Announces Positive Cardiac Safety Data From Picoplatin Phase 1 Trial Supporting NDA Filing
Poniard Pharmaceuticals, Inc. (Nasdaq: PARD), a biopharmaceutical company focused on innovative oncology therapies, announced results from a Phase 1 cardiac safety study of picoplatin, a new generation platinum-based chemotherapy agent and the Company"s lead product candidate. The Company worked collaboratively with the U.S. Food and Drug Administration (FDA) to design this study, which is required for new chemical entities.
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Evidence Supports Use Of Web- And Computer-Based Programs To Help Adults Quit Smoking
Available evidence supports the use of online or other computer-based smoking cessation programs for helping adults quit smoking, according to a meta-analysis of previously published studies appearing in the May 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
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Study Of Infant Sleep Patterns And Parenting
Infants" sleep patterns and their parents" influence on it are the focus of the SIESTA II project, supported by a five-year, $2.67 million grant from the National Institute of Child Health and Human Development to Douglas M. Teti, professor of human development and psychology, Penn State.
Public Health

Grant Will Support Comparative Effectiveness Research On Depression

The National Institute of Mental Health has awarded Group Health a $1 million stimulus grant to research more effective treatment for depression. The award is part of the federal stimulus funds from ARRA, the American Recovery and Reinvestment Act of 2009. The project will evaluate a new method for studying the effectiveness of treatments for depression. It will use electronic medical records to follow how individuals respond to different treatments across time. The study will track health outcomes against various factors in hundreds of Group Health patients" records, coded to protect privacy. "As long as antidepressants have existed, researchers have sought ways to match patients with the specific treatments that suit them best," explained Group Health psychiatrist Greg Simon, MD, MPH. He is also a senior investigator at Group Health"s research institute, Group Health Center for Health Studies. During the two-year study, Simon and his research team will plan a second, much larger investigation. If funded, it will be conducted by mental health researchers at several large health plans in the HMO Research Network. The Network is a consortium of nonproprietary public-interest research institutes with access to data on 10 million people nationwide. Simon"s study is an example of Group Health"s ongoing research on "comparative effectiveness." That means figuring out how well tests, treatments, and preventive actions work in real clinical settings. The federal government is calling for comparative effectiveness research as a way to base medicine - and health care reform - on the best available evidence. The goal: ensuring that people receive the most effective health care available. Researchers at Group Health Center for Health Studies have applied for other grants from the stimulus funds as well. This is the first of these grants to be awarded. Simon has participated in several well-known studies of depression, including its links to obesity and how to deliver therapy over the phone, online, and through workplace-based programs. Rebecca Hughes Group Health Cooperative Center for Health Studies


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