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NIST Researchers 'All Aglow' Over New Test Of Toxin Strength
A new National Institute of Standards and Technology (NIST) assay using a "glow or no glow" technique may soon help the U.S. Department of Homeland Security (DHS) defend the nation against a spectrum of biological weapons that could be used in a terrorist attack. One very dangerous toxin on the list is ricin, a protein derived from castor beans that is lethal in doses as small as 500 micrograms - about the size of a grain of salt.
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Roche And Google.org Start Initiative For Early Discovery Of New Diseases
Roche and Google.org recently started a joint project to demonstrate the feasibility of developing a multidisciplinary surveillance, research and response system. This system will enhance the ability to predict and prevent emerging infectious diseases in East Africa. Roche has donated a Genome Sequencer FLX system as backbone of this project."We are proud to work with Google.org, and the dedicated research organizations in Kenya to bring this technology to a region of the world where novel viruses frequently emerge. We are confident that access to the 454 Sequencing Systems will improve monitoring of novel infectious diseases and enable faster discovery in case of an outbreak," said Chris McLeod, CEO of 454 Life Sciences, a member of the Roche Group.
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Health Reform Price Tag Has Dems Scrambling To Lower Cost
The up to $1.6 trillion price tag for one version of health care reform has left Democrats scrambling to find a way to rein in costs while not sacrificing the basic tenets of a plan they favor, The Washington Post reports.
Sexual Health

Lifelong Cancer Risk For Patients Treated For Childhood Cancer

Childhood cancer survivors have a persistent and high risk for a second primary cancer throughout their lives, according to a new study published in the May 26 online issue of the Journal of the National Cancer Institute. Previous studies established that second primary cancer risk after treatment in childhood is higher than that in the general population, but follow-up was restricted to a few decades and the incidence in long-term survivors was rarely investigated. This study presents data for incidence of second cancers among childhood cancer patients in the Nordic countries over a full age range, from birth to age 79. In the study, JÃñrgen H. Olsen, M.D., of the Institute of Cancer Epidemiology, Danish Cancer Society, in Copenhagen, Denmark, and colleagues studied a cohort of 47,697 people who were diagnosed with cancer prior to the age of 20, from 1943 to 2005. Members of the cohort were followed for subsequent primary cancers listed in registries, and the age-specific risk pattern of the survivors was compared with that of the national populations using country and sex standardized incidence ratios (SIRs). The researchers found that the observed incidence rate of new primary cancers was higher than the expected rates, and the relative risk of second primary cancers was statistically significantly increased in all age groups. A total of 1,180 second primary cancers were observed in 1,088 persons, yielding a SIR of 3.3, with the brain as the most common site. They also found that the relative risk for second primary cancers in male survivors was statistically significantly higher than in female survivors. "This study quantified long-term temporal patterns of increased risk of cancer at specific sites in survivors of childhood cancer," the authors write. "The results may be useful in the screening and care of these individuals." Citation: Olsen et al. Lifelong Cancer Incidence in 47 697 Patients Treated for Childhood Cancer in the Nordic Countries. J Natl Cancer Inst 2009, 101: 806-813. Steve Graff Journal of the National Cancer Institute


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