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Copy Number Analysis Indicates Monoclonal Origin Of Lethal Metastatic Prostate Cancer
BERKELEY, CA (UroToday.com) - I was trained and board certified as a urologist (University of Virginia) and pathologist (Cornell and UVA) and arrived at Johns Hopkins in 1991 to do a research fellowship with Dr. William B. Isaacs, funded by the American Foundation for Urologic Disease (now the AUA Foundation).
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Columnists Respond To Selection Of Sotomayor As Supreme Court Nominee
The New York Times, Washington Post and Washington Times recently published opinion pieces on President Obama"s nomination of Judge Sonia Sotomayor to the Supreme Court. Summaries appear below.~ David Brooks, New York Times: "Supreme Court justices, like all of us, are emotional intuitionists" because "they begin their decision-making processes with certain models in their heads," Times columnist Brooks writes, adding that "[t]hese are models of how the world works and should work, which have been idiosyncratically ingrained by genes, culture, education, parents and events," and which "shape the way judges perceive the world." Therefore, the "crucial question in evaluating a potential Supreme Court justice ... is not whether she relies on empathy or emotion, but how she does so," according to Brooks. He writes that Sotomayor "will be a good justice if she can empathize with the many types of people and actions involved in a case, but a bad justice if she can only empathize with one type, one ethnic group or one social class." He concludes, "It"s not whether judges rely on emotion and empathy, it"s how they educate their sentiments within the discipline of manners and morals, tradition and practice" (Brooks, New York Times, 5/29).~ Michael Gerson, Washington Post: By opposing Sotomayor"s confirmation, Republicans could be entering "a trap" by "further alienating Hispanic voters the GOP has recently driven away in droves," which might "confirm an image of Republicans as the party of the male and pale," columnist Gerson writes in a Post opinion piece. He continues, "Barring unforeseen ethical revelations, opposition to Sotomayor seems both politically risky and ultimately futile." However, "Republicans must still enter the trap -- with open eyes and no expectation of gain -- not to defeat a nominee but to maintain a principle" that the court "should be a place where all are judged impartially, as individuals," Gerson writes. He continues that the "Obama/Sotomayor doctrine of empathy challenges this long-established belief," and this "is not a minor matter." According to Gerson, "Concerns about the doctrine of empathy will not defeat Sotomayor -- and perhaps they should not defeat her." However, the "problems raised by selective empathy require a substantive (not harsh or personal) national debate -- and this requires Republicans to carefully, warily, enter Obama"s trap" (Gerson, Washington Post, 5/29).~ Michael Kinsley, Washington Post: "What conservative Republicans don"t like about the Supreme Court can be summarized as three, or maybe four, A"s: abortion, affirmative action and activism," columnist Kinsley writes in a Post opinion piece. He adds that "[r]ecent Republican platforms have pledged to appoint judges who not only will overturn Roe [v. Wade] but will make clear that fetuses have the same rights as people under the 14th Amendment"s guarantee of "equal protection of the laws."" Kinsley continues that supporters of Roe "clearly represent the "activist" side," while opponents of the decision "are right that Roe represents the highest tide of Warren Court activism." However, this "doesn"t mean the critics of Roe are right on the merits;" rather, it means that ""activism" is a near-worthless concept, and comparative activism is nonsense," Kinsley writes. He continues, "Although I am pro-choice, Roe makes me unhappy because it was poorly reasoned, not because it "went further" than other decisions." According to Kinsley, "many opponents of Roe would not be satisfied with merely seeing it overturned and the issue returned to the states," and, in fact, the GOP platform "effectively calls for a litmus test for judges: Will they rule abortion illegal in all 50 states no matter what the people want?" He continues, "Now that would be judicial activism with a vengeance" (Kinsley, Washington Post, 5/29).~ Eugene Robinson, Washington Post: The fact that Sotomayor "is a proud and accomplished Latina" apparently "drives some prominent Republicans into a s
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$10 Million European Community Water And Sanitation Project Underway In Iraq; UNICEF Relocates Country Office To Baghdad
- A $10 million project funded by the European Community to improve Iraq"s water and sanitation services is underway. Implemented by UNICEF in collaboration with the Ministry of Municipalities and Public Works and the Ministry of Municipalities in Kurdistan, the project will increase the government"s provision of services as well as strengthen their capacity to manage and develop Iraq"s water and sanitation sector.
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Limiting Work Hours Of Medical Residents Could Cost $1.6 Billion Annually, Study Finds

New recommendations to limit the work hours of medical residents could cost the nation"s teaching hospitals about $1.6 billion annually to hire substitute workers, according to a new report from the RAND Corporation and UCLA. While society may benefit if such changes reduce medical errors as intended, limiting trainee workloads would create a substantial new expense for academic medical centers, according to the study published in the May 21 edition of the New England Journal of Medicine. "Adopting new restrictions on the work hours of physicians in training would impose a substantial new cost on the nation"s 8,500 physician training programs," said lead author Dr. Teryl K. Nuckols, an internist at the David Geffen School of Medicine at UCLA and a researcher at RAND, a nonprofit research organization. "There is no obvious way to pay for these changes so that"s one major issue that must be addressed." In December, the Institute of Medicine released a report calling for revisions to medical residents" workloads to decrease the chances of fatigue-related medical errors and to enhance the learning environment. Recommendations include requiring prolonged shifts to include protected time for sleep, reducing to 16 hours the duration of time residents can work without protected time for sleep, reducing residents" workload, and increasing the number of days residents must have off. Graduate medical education programs traditionally have required residents to work long hours, often more than 100 hours per week. Such training programs generally run three to seven years following medical school. The study from RAND Health and UCLA provides new details about the potential costs and clinical implications of the Institute of Medicine recommendations, expanding upon a cost analysis described in the original report. Should the recommendations be adopted, researchers say teaching hospitals would need to make up for residents" shorter work hours by either hiring other providers such as physician assistants to do the work or by expanding the number of residency positions. While adding residency slots could help ease physician shortages in some specialties, it also could lead to oversupply in others, according to the study. Researchers estimate that residency positions would need to grow by about 8 percent overall to meet staffing needs under the IOM recommendations. "The trainees who are working more than the proposed limits would allow are not necessarily in the specialties where more physicians are needed," Nuckols said. "For example, pediatric residents work a lot of hours, but there is no evidence that there are too few pediatricians." Researchers estimate that adopting the Institute of Medicine"s recommendations would cost each major teaching hospital about $3.2 million annually on average. That is higher than other proven quality improvement efforts for hospitals such as computerized physician order entry and medication bar-coding systems. But it would be less expensive than other proposals, such as requiring that there be one nurse for every four patients. One study of shorter work shifts suggests that reducing resident work hours could cut serious medical errors by 25 percent in medical intensive care units. But few errors cause injury and the effects could be different in other clinical settings, according to the study. In addition, revising work rules could prompt other types of medical errors as the care of hospitalized patients is more-frequently handed from one provider to another. Researchers say adopting the recommendations of the IOM report would be more expensive for teaching hospitals than a major revision of resident work hours adopted by training programs five years ago. Those rules say that residents should not work more than an average of 80 hours per week, among other limits. "Residency programs already have picked much of the low-hanging fruit by reducing the non-educational duties placed on residents," Nuckols said. "Further changes will require that hospitals hire professionals with high levels of training, such as nurse practitioners and physicians, and that will be expensive." Other authors of the study are Dr. Jose J. Escarce of RAND and UCLA, Dr. Jay Bhattacharya of Stanford University, and Dianne Miller Wolman and Cheryl Ulmer of the Institute of Medicine. Support for the study was provided by the Institute of Medicine, under contract to the federal Agency for Healthcare Research and Quality. Warren Robak RAND Corporation


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