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They Are Young And Need The Job: A Second Chance For Dangerous T Cells
The immune system"s T-cells react to foreign protein fragments and therefore are crucial to combating viruses and bacteria. Errant cells that attack the body"s own material are in most cases driven to cell death. Some of these autoreactive T-cells, however, undergo a kind of reeducation to become "regulatory T-cells" that keep other autoreactive T-cells under control. A group led by immunologist Professor Ludger Klein of LMU Munich has now shown that the developmental stage of an autoreactive T-cell is decisive to its ultimate destiny. Young autoreactive T-cells are very readily reeducated into regulatory T-cells. Under identical conditions, however, older T-cells become fully activated and can cause damage - they are in a way resistant to reeducation. "We now intend to study at the molecular level what makes a T-cell accessible for reeducation," said Klein, "because then it may be possible to convert even normal adult T-cells, which can be obtained easily and in great numbers from blood. Possibly, they could then be used as regulatory T-cells in therapies for autoimmune diseases such as type-1 diabetes or multiple sclerosis: these are diseases that are triggered by uncontrolled autoreactive T-cells." (PNAS, 10 June 2009)
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Office Of Tobacco Control Welcomes Removal Of All Tobacco Advertising From Retail Premises, Ireland
The Office of Tobacco Control (OTC) today (July 1, 2009) welcomed the commencement by the Department of Health and Children of further provisions of the Public Health (Tobacco) Acts, 2002 and 2004. The key provisions now commenced are:
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Green Tea Compounds Reduced Prostate Cancer Markers, Study
US researchers found that men with prostate cancer who consumed a mix of polyphenols found in green tea experienced a significant reduction in
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MS Society Pleased With Government Recognition Of Crisis In Social Care

The government"s Green Paper "Shaping the Future of Care Together" has been welcomed by the MS Society as the radical step necessary to address the crisis in social care. Announced on Tuesday, the bold proposals set out a vision for a care system as important as the NHS, billed as the "National Care Service", which could potentially bring an end to the postcode lottery in care and improve its quality. The Green Paper presents proposals for the long term funding of better care for the growing number of older people, and people with long-term conditions such as multiple sclerosis (MS). Dan Berry, MS Society Head of Policy and Campaigns, said: "This is a bold set of proposals for care reform. People with MS were hoping for a clear and ambitious vision from the Government and that is what these proposals represent. "A lot of the detail is missing, however, and it is likely to be years before these proposals become a reality, while people with MS continue to fight for access to adequate social care now. "Over the next few months, and up to the next general election, I hope the government uses the opportunity to have a frank discussion with those people who need care now and those who may do in the future, on how to bring about the res needed in a way that"s fair to all." MS Society


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