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Computer System For Dementia Patients
The labour force in the health services is shrinking, there are more and more old people, and a very high proportion of them are plagued by deteriorating short- and long-term memory. All this has created a need for computer-based solutions that will enable elderly people to live safely in their own homes, but at the same time, the technology needed to take special care of them is expensive. On top of this, different standards for home sensors create problems.
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Potential Prenatal Origins For Poor Sleep In Children
A study, "Prenatal Origins of Poor Sleep in Children," in the Aug.1 issue of the journal SLEEP found that alcohol consumption during pregnancy and small body size at birth predict poorer sleep and higher risk of sleep disturbances in 8-year-old children born at term. Findings are clinically significant, as poor sleep and sleep disturbances in children are associated with obesity, depressive symptoms, attention deficit hyperactivity disorder, and poor neurobehavioral functioning.
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Generation Of A Severe Memory-Deficit Mutant Mouse By Exclusively Eliminating The Kinase Activity Of CaMKIIalpha
Ca2+/calmodulin-dependent protein kinase II alpha (CaMKII alpha) is an enzyme that adds phosphates to a variety of protein substrates to modify their functions. CaMKII alpha is enriched in the hippocampus, the memory center of the brain, and is believed to be an essential mediator of activity-dependent synaptic plasticity and memory functions. However, the causative role of the enzymatic activity of CaMKII alpha in such processes has not been demonstrated yet, because this enzyme has multiple protein functions other than the kinase activity. A Japanese research group, led by Dr Yoko Yamagata of the National Institute for Physiological Sciences, Japan, has successfully generated a novel kinase-dead mutant mouse of the CaMKII alpha gene that completely and exclusively lacks its kinase activity. They examined hippocampal synaptic plasticity and behavioral learning of the mouse, and found a severe deficit in both processes. They reported their findings in the Journal of Neuroscience, published on June 10, 2009.
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Marco Pierre White Supports Global Call To Action To Reduce Dietary Salt Intake And Improve Heart Health On World Hypertension Day

Internationally acclaimed Michelin-starred chef Marco Pierre White is supporting a global campaign launched today by the World Hypertension League to encourage more people to adopt a healthy, low salt diet to tackle the problem of high blood pressure. High blood pressure affects over 1.5 billion people around the world1. Excess salt raises blood pressure2, which is the number one risk factor for cardiovascular disease, the number one cause of death worldwide3. More than 40 countries are participating in a series of public events to support World Hypertension Day 2009, now in its fifth year. These events aim to highlight that reducing daily salt intake by half could save approximately 2.5 million people a year dying from strokes and heart attacks worldwide1. Marco explains: "An individual"s palette is normally established during childhood and by the time we become an adult we have already acquired a strong taste for salt, which can result in us eating more than we need. I am supporting World Hypertension Day to encourage people to manage their salt intake more effectively. We can all take simple steps to reduce the level of salt in our diets such as avoiding processed, pre-packaged foods and using citrus fruit, herbs and spices instead of salt to enhance flavour." In many countries, the daily salt intake is around 12g - more than double the amount considered necessary by the World Health Organisation (WHO)4. Research has shown that in addition to restricting salt intake there are a number of lifestyle changes, such as taking regular exercise, maintaining a healthy weight, giving up smoking and eating healthy foods lower in salt, which can contribute to the prevention of high blood pressure and reduction of cardiovascular risk5. Dr Arun Chockalingam, Secretary General of the World Hypertension League said: "The goal of this year"s World Hypertension Day is to encourage people to think about the amount of salt in their diet and the impact of excess salt on their blood pressure. A small reduction in salt consumption can be extremely effective in reducing blood pressure and its associated cardiovascular risks, and will result in a major improvement in public health." High blood pressure occurs when there is an increase in blood volume and/or blood vessels constrict, forcing the heart to work harder to pump blood to supply oxygen and nutrients to various organs in the body. Salt causes the body to retain water, with excess levels resulting in an increase in blood volume and high blood pressure. High blood pressure in turn causes hardening and thickening of blood vessels, therefore increasing the stress on the heart which has to pump blood through narrowed arteries. In some cases, this can lead to heart failure or inability of the heart to pump sufficient blood to meet the demands of the body. World Hypertension Day, initiated by the World Hypertension League in 2005, is an international event with public activities taking place around the world to raise awareness of the health importance of good blood pressure control. World Hypertension Day is supported globally by Novartis. For more information about World Hypertension Day events in your country, contact your national hypertension society or visit our website at http://www.worldhypertensionleague.org References 1 World Hypertension League Brochure 2009. Available here. Last accessed April 2009. 2 Sacks FM et al. Effects on blood pressure of reduced dietary sodium and the dietary approaches to stop hypertension. New England Journal of Medicine. 2001;344:3-10. 3 World Health Organization. Cardiovascular disease factsheet. Available at: http://www.who.int/mediacentre/factsheets/fs317/en/index.html. Last accessed April 2009. 4 Feng JH, MacGregor GA. How far should salt intake be reduced. Hypertension. 2003;42:1093-1099. 5 Writing Group of the PREMIER Collaborative Research Group. Effects of comprehensive lifestyle modification on blood pressure control: main results of the PREMIER clinical trial. JAMA. 2003;289(10):2083-2093. World Hypertension League


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