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Informa Announces A New Award For Best Review Paper
The editors of Disability & Rehabilitation and its sister publication, Disability & Rehabilitation: Assistive Technology have announced an annual award which will be given for the best review paper published in either of the two journals. Commencing in 2009, the Informa Best Review Paper Award will recognise valuable, high-impact research in the fields of disability, rehabilitation and assistive technology.
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Daily Temperature Shifts May Alter Malaria Patterns
Daytime temperature fluctuations greatly alter the incubation period of malaria parasites in mosquitoes and alter transmission rates of the disease. Consideration of these fluctuations reveals a more accurate picture of climate change"s impact on malaria.
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Abbott And AstraZeneca Submit New Drug Application To The FDA For CERTRIAD™, An Investigational Treatment For Mixed Dyslipidemia
Abbott Park, Illinois (NYSE: ABT) and London, UK - Abbott and AstraZeneca announced that the companies have submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for an investigational compound for the treatment of mixed dyslipidemia, a combination of two or more lipid abnormalities including high LDL- cholesterol (the "bad" cholesterol), high triglycerides and low HDL-cholesterol (the "good" cholesterol). The NDA submission for this investigational compound, containing the active ingredients of CRESTOR® (rosuvastatin calcium) and TRILIPIX® (fenofibric acid), is supported by data from multiple studies, including efficacy and safety studies with the 5mg, 10mg and 20mg doses of rosuvastatin combined with fenofibric acid. Pending approval of the NDA, the treatment will be marketed as CERTRIAD™.
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Poor Sleep Quality And Increased Risk Of Death

Quality, in addition to quantity, is important for maintaining health, according to a research abstract that will be presented on Wednesday, June 10, at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies. Results indicate that over the average follow-up of eight years, 854 of the 5,614 participants died. Two sleep-stage transition types were associated with higher mortality risk: wake-to-non-REM and non-REM-to-wake. According to lead author Alison Laffan, PhD, former graduate student at the Johns Hopkins Bloomberg School of Public Health and current post-doctoral fellow at the California Pacific Medical Center in San Francisco, Calif., mounting evidence from a number of studies shows that poor sleep increases risk for adverse health outcomes. "In light of this growing body of evidence, people should strive to maintain good sleep habits, such as going to bed and getting up at the same time each day and sleeping for seven to eight hours each night," said Laffan. The study involved data from 5,614 Sleep Heart Health Study participants who underwent overnight polysomnography to characterize sleep. Health outcomes were monitored for the following eight years. Sleep fragmentation was defined using an index of the number of sleep stage transitions per hour of sleep. In addition to a composite transition index, indexes of each of the six types of transitions were also tested. The relative risk of death as a function of each transition index was calculated using proportional hazards models, adjusting for age, gender, body mass index, race, hypertension, cardiovascular disease, smoking status, respiratory disturbance index and arousal index. According to the authors of the study, obstructive sleep apnea (OSA), a major cause of sleep fragmentation, has been linked to increased risk for all-cause mortality; however, most studies have not directly measured fragmentation. Findings of this study were able to directly measure the relationship between sleep fragmentation and mortality. Abstract Title: Sleep Fragmentation Predicts All-Cause Mortality in a Cohort of Middle Aged and Older Adults Presentation Date: Wednesday, June 10 Category: Aging Abstract ID: 0363 Kelly Wagner American Academy of Sleep Medicine


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