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Rapid, Pain-Free Test For Men Offered By New Chlamydia Test
A new urine test developed with funding from the Wellcome Trust will allow doctors to diagnose Chlamydia infection in men within the hour, improving the ability to successfully treat the infection on the spot and prevent re-transmission.
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Pregnancy Rates Unaffected By Single Thawed Embryo Transfer After PGD
Transferring just one embryo at a time to a woman"s womb after embryos have undergone preimplantation genetic diagnosis (PGD) and freezing at the blastocyst stage has become a real option after researchers achieved pregnancy rates that were as good as those for blastocysts that had not had a cell removed for PGD before freezing. Their results mean that it will be possible to reduce the number of multiple pregnancies after PGD and the consequent complications associated with these pregnancies.
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Lobbying Draws On Ranks Of Former Government Officials, Health Industry Coffers
"The nation"s largest insurers, hospitals and medical groups have hired more than 350 former government staff members and retired members of Congress in hopes of influencing their old bosses and colleagues, according to an analysis of lobbying disclosures and other records," the Washington Post reports. The Post"s analysis of lobbying disclosure records shows that three-quarters of major health firms have hired an insider to lobby on their behalf; half of those insiders once worked for the key senators and congressional committees that are now shaping the reform proposals.
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Rampant Helper Syndrome Methane-producing Molecule Can Also Repair DNA

Catalysts assist in chemical reactions without undergoing any alteration of their own. In the cells of living organisms, proteins perform this important function. They carry out the metabolism fundamental to all living processes. Proteins are instrumental in cellular respiration, they for instance reduce oxygen to water and oxidize food into carbon dioxide. This releases the energy that makes life possible at all. Proteins cannot perform these functions on their own. They depend on small helper molecules. Such molecules are stored inside special pockets in the proteins and carry out essential metabolic functions. The living organism itself produces many of these helpers. Others like vitamins must be obtained from food. Severe vitamin deficiencies are a harsh reminder of how essential these molecules are. Methanogenic bacteria have quite an exceptional task to accomplish: They have to produce methane. In terms of chemistry, this is no mean feat. Methane production is currently one of the most hotly pursued goals for the purposes of renewable energy. It is also a serious greenhouse gas. Enzymatic methane production involves the tiny molecule deazaflavin, known as cofactor F0 or cofactor F420. This cofactor is stored inside special proteins of methanogenic bacteria, and is essential for methane biosynthesis. Cofactor F0/F420 is a small molecule that, until now, has only been found in methanogenic bacteria. It is regarded as the signature molecule for such species. "We have now shown that this picture is not entirely true," Carell says. "This cofactor is significantly more widespread in the biosphere than previously assumed. Most importantly, it also occurs in higher organisms, the so-called eukaryotes. But in these, it performs a completely different task." As the researchers were able to demonstrate, the cofactor is involved in DNA repair processes. Specifically, repair of UV damage to the DNA molecule. Plants and many other organisms that are exposed to intense sunlight must cope with an enormous degree of damage to their genes. To repair those mutations, they need the help of complex enzymes. These photolyases in turn require cofactor FAD aka vitamin B2 to accomplish this function. It has long been suspected that these crucial enzymes require yet another cofactor to provide the energy that DNA repair requires. "We have now shown that, in many organisms, this cofactor is F0/F420," Carell reports. "This molecule has been conclusively detected in DNA repair enzymes of Drosophila melanogaster, the fruit fly. Not long ago, another research group even postulated that F0/F420 is co-responsible for DNA repair in plants. Our view of cofactor F420 as a signature molecule for methanogenic species has therefore radically changed: this cofactor is widespread and it is essential for both methane synthesis and for DNA repair." Professor Thomas Carell is speaker of the "Center for Integrated Protein Science Munich (CiPSM)" center of excellence which supported this research. (suwe) Ludwig-Maximilians-Universitaet Muenchen


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