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House Recesses, Democrats Reflect On Accomplishments And What's Ahead
House Democrats celebrated late last week the passage of a health reform bill out of the House Energy and Commerce Committee, but they still face a lot of work when they return in September, Roll Call reports.
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Meeting To Examine Human Behavior And The Threat Of Disease
As swine flu spread from Mexico to Texas and then fanned out farther in the United States, Americans began to alter their behavior. Families kept children home from school, postponed trips to the mall, and stayed home instead of eating out. In so doing, the American population may have inadvertently altered the behavior of the pathogen itself.
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Amyloid Aggregations And Tau Pathology Reflected By Cortical Thickness In The Default Network Of MCI And AD
Alzheimer"s disease patients show a relentless decline in memory over the course of the disease, which is accompanied by both brain atrophy and by characteristic deposits in the brain tissue called amyloid plaques and neurofibrillary tangles. Researchers from the Chinese Academy of Sciences studied a large database, collected in the US, of patients with Alzheimer"s or memory complaints who had MRI scans and had spinal taps to collect cerebrospinal fluid, which is in the brain and spinal chord. By examining the CFS they could measure the amounts of the substances that make p plaques and tangles, and related this to brain atrophy. They found that the amount of plaque and tangle-producing chemicals in the cerebrospinal fluid correlated with brain tissue loss in selective regions of the brain which are typically affected in Alzheimer"s disease. The brains in these regions had thinned out suggesting that brain cells had died. These regions are important for memory and are typically active when the brain is at rest. Using these techniques may ultimately help identify early markers of disease in Alzheimer"s, potentially indicating who is likely to develop Alzheimer"s before memory loss is critical.
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Study Sees Transient Heart Dysfunction In Some Long-Distance Runners

A new study using advanced cardiac imaging technology indicates that cardiac abnormalities experienced by some marathon runners following competition are temporary, and do not result in damage to the heart muscle. The study, conducted by researchers at the University of Manitoba, marked the first use of cardiac magnetic resonance imaging, or CMR, in a post-marathon setting. The research was presented on Sunday, May 17, at the 105th International Conference of the American Thoracic Society in San Diego. "Although previous studies of marathon runners have demonstrated biochemical evidence of cardiac injury and have correlated these findings with echocardiographic evidence of cardiac dysfunction, this was the first time CMR has been used to further evaluate and understand the effects of marathon running on the heart," said study investigator Davinder S. Jassal, M.D., assistant professor of cardiology, radiology and physiology at St. Boniface General Hospital Research Centre in Winnipeg. The study examined the cardiac health of 14 runners who participated in the full 2008 Manitoba Marathon in Winnipeg, Canada. All runners were classified, for purposes of the study, as "non-elite," meaning they participated on a casual, non-professional basis, with limited or no training. Prior to the marathon, each study participant underwent a comprehensive health screening, including blood tests to determine the levels of cardiac biomarkers, factors present in the blood that reflect the health of the heart muscle. Following the race, additional blood samples were taken and echocardiograms and CMR were performed. Earlier studies have confirmed that cardiac biomarkers are elevated in many casual, non-professional athletes following competition, indicating possible damage to the heart muscle. In this study, echocardiograms and CMR performed immediately after competition revealed abnormalities, including irregularities in diastolic filling (relaxation abnormalities) on both sides of the heart and a decrease from 64 percent to 43 percent in the pumping function of the right ventricle. Although the cardiac biomarkers were elevated post marathon, there was no evidence of direct permanent injury to the heart muscle on CMR imaging. "By using CMR, we were able to definitively show that these fluctuations do not result in any true damage of the heart, and the right ventricular dysfunction is transient, recovering one week following the race," Dr. Jassal noted. The researchers are planning additional studies to determine whether these abnormalities may result in permanent damage in runners who participate in more than one marathon during a 12-month period. Keely Savoie American Thoracic Society


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