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Can Virtual Humans And Micro-lungs Bring The End Of Animal Research?
Science fact meets science fiction as experts imagine a future without animal research and how we might get there - at this year"s Cheltenham Science Festival.
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Public Health Experts Discuss Infectious Diseases Threats At News Conference
Updates on the impact of sexually transmitted diseases, infection risk from animals in the home and public settings, seasonal and H1N1 influenza, and foodborne diseases were presented today at a news conference at the National Press Club in Washington, D.C. The news conference was sponsored by the National Foundation for Infectious Diseases (NFID).
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Shedding Light On Esophageal Disease
Canadian Light (CLS) staff scientist Luca Quaroni and Dr. Alan Casson, Head of the Department of Surgery at the University of Saskatchewan (U of S) used the synchrotron"s infrared microscope to identify tissue afflicted with a condition known as Barrett"s Esophagus from chemical fingerprints associated with the disease, which can lead to esophageal cancer. The finding is published in the June, 2009 issue of the Royal Society of Chemistry journal, The Analyst.
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Technique That Improves Anterior Cruciate Ligament Surgery

Surgeons from Hospital for Special Surgery in New York have identified a drilling technique that improves the outcome of surgery to reconstruct the anterior cruciate ligament (ACL). The news is being presented during the annual meeting of the American Orthopedic Society for Sports Medicine, June 9 -12, in Keystone. Colo. "We found that the anatomy was better reproduced with the anteromedial portal drilling technique compared to the transtibial technique," said Asheesh Bedi, M.D., a fellow in sports medicine and shoulder surgery at Hospital for Special Surgery who was involved with the study. In recent years, an improved understanding of the anatomy of the ACL has allowed surgeons to refine techniques to reconstruct the ACL. Investigators at Hospital for Special Surgery (HSS) set out to compare the outcomes of surgeries using two common techniques. "The goal in repairing the ACL is to recreate the normal anatomy, and there are a variety of different techniques to prepare tunnels for ACL reconstruction that have evolved over time," said Dr. Bedi. "The focus of the study was to compare two very common techniques in terms of their ability to reproduce the native ligament anatomy and restore the stability of the knee after reconstruction in a cadaveric model." The investigators used ten matched cadaveric knees to directly compare the transtibial and anteromedial portal drilling technique. The researchers found that the transtibial technique could not reproduce the position of the ACL, whereas the anteromedial portal drilling technique could better restore the native anatomy. The transtibial technique also presented additional concerns. "In preparing the femoral tunnel using the transtibial technique, the tibial tunnel is inadvertently re-reamed as much as 30 percent and can lead to significant time-zero tunnel expansion," Dr. Bedi said. The transtibial reconstruction also performed inferiorly to the medial portal on a number of biomechanical parameters of stability assessed with computer navigation. "This study clearly demonstrates that restoring the anatomy of the ACL and the stability of the knee is far superior when the femoral socket is reamed through the anteromedial portal rather than the tibial tunnel, as has been traditionally done by most surgeons," said David W. Altchek, M.D., attending orthopedic surgeon and co-chief of the Sports Medicine and Shoulder Service at HSS. "HSS is an international leader in this innovative solution toward further improving patient outcomes in ACL surgery." According to Dr. Bedi, the work has translated into modified techniques in the operating room at HSS, where more than 800 ACL surgeries are performed each year. Tears of the ACL are quite common, with between 70,000 and 80,000 reported each year in the United States. Other researchers involved in the study are Volker Musahl, M.D., Volker Steuber, M.D., Daniel Kendoff, M.D., Answorth A. Allen, M.D., and Andrew D. Pearle, M.D., all with the Sports Medicine and Shoulder Service at HSS. Phyllis Fisher Hospital for Special Surgery


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