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ExonHit Announces Last Patient Out For EHT 0202 Phase IIa Study In Alzheimer's
ExonHit Therapeutics (Paris:ALEHT) announced that clinical testing of EHT 0202, its lead therapeutic compound in Alzheimer"s disease, is progressing well. Final patient dosing for the Phase IIa proof-of-concept clinical trial assessing EHT 0202 in patients with Alzheimer"s disease is completed.
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Are Imaging Features Of Hepatic Angiomyolipoma Related To Its Clinical Setting?
This study consisted of 10 patients (three male and seven female) with hepatic angiomyolipoma, with a mean age of 55.1 years (age range, 19-78 years). Of these patients, dynamic contrast CT showed hepatic angiomyolipoma as a hypervascular mass with intratumoral fatty density, absence of a capsule, and prominent central vessels in six sporadic cases, and multiple, small hepatic angiomyolipomas, with or without a fat component in four cases with tuberous sclerosis complex (TSC). Lymphangioleiomyomatosis (LAM) and multiple hepatic angiomyolipomas were found in one patient with TSC.
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Early Signs Of Cardiovascular Disease Increased By Childhood Obesity
By as early as 7 years of age, being obese may raise a child"s future risk of heart disease and stroke, even without the presence of other cardiovascular risk factors such as high blood pressure, a new study found. The results were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.
Public Health

Testing For Norovirus And Enterovirus Is Becoming Increasingly Important And Commonplace

High profile outbreaks associated with the viruses have kept EMSL Analytical scientists busy. Pollution of rivers and recreational waters by sewage and animal fecal waste has led to a number of high profile human gastrointestinal infections in recent years. Many of these same contaminants can be passed from human to human by direct contact with secretions from an infected person or by contacting contaminated surfaces. Monitoring environmental microorganisms such as bacteria and viruses is an important method for the prevention of human diseases. Frequent outbreaks of the two viruses, enterovirus and norovirus; have caused particularly serious environmental health concerns in numerous high profile cases. According to the CDC, "Noroviruses are highly contagious and as few as 10 viral particles may be sufficient to infect an individual." Enteroviruses are believed to cause between 30 and 50 million infections in the United States alone each year. EMSL Analytical, a leading environmental testing laboratory, has been busy utilizing advanced PCR technologies to test environmental samples for the viruses. Advances in testing methods have produced several PCR-based methods that now do not require animal cultures for analysis, improving the analytical process. "In the PCR-based rapid detection methods, virus particles in water samples are captured on aluminum chloride coated negative charged HA membranes," reported Charlie Li, Ph.D., PCR Laboratory Director at EMSL Analytical. "The viruses are then eluted out and concentrated using ultra-filtration. Viral RNA is then isolated from the eluted virus. Using a one-step reverse transcription real-time PCR, virus RNA are converted to DNA, then detected with a sensitive and specific real-time PCR." Clearly, the tests provide an approach for rapid monitoring of the viruses and other additional human viral pathogens. To learn more about norovirus or enterovirus contact EMSL Analytical at 800-220-3675 or visit http://www.EMSL.com. EMSL Analytical, Inc.


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