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Researchers Find A Way To Reduce Patient Radiation Dose During Pulmonary CT Angiography
While screening for possible pulmonary emboli using pulmonary CT angiography, a new study shows that radiologists can effectively lower the patient radiation dose by approximately 44% and improve vascular enhancement without deterioration of image quality, according to a study performed at Brigham and Women"s Hospital and Harvard Medical School, Boston, MA.
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What Is The Difference Between Hip Resurfacing And Total Hip Replacement?
If hip resurfacing is an option, the surgeon will simply reshape the damaged surface of the femoral ball and then cover it with a round metal cap. The limitation here is that the procedure only works for bone that is not too damaged by arthritis. Generally speaking, surface replacements are not performed on patients with serious arthritic conditions, because if the bone is not strong enough, there is a small but real risk of fracturing. Therefore the average age of resurfacing patients may be 50 years or younger. Statistically, the resurfacing operation is an option for about 7 out of a 100 patients.
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House Democrats May Rethink Tax Increases
Democratic leaders may scale back a plan to tax the highest American earners, The New York Times reports.
Mental Health

Trapping Immune Cells In The Uterus Prevents Anti-fetal Immunity

Why the immune system of a pregnant woman does not attack her developing fetus is one of most remarkable features of pregnancy, and several underlying mechanisms have been described. However, Adrian Erlebacher and colleagues, at the New York University School of Medicine, New York, have now identified a new mechanism to explain why the mouse maternal immune system does not attack the fetuses. Once an embryo implants into the wall of the uterus, a cellular structure known as the decidua forms around the embryo and placenta. In the study, the formation of the decidua was found to prevent immune sentinel cells known as DCs from leaving the maternal/fetal interface and traveling to the local lymph nodes to activate an immune response toward the fetus. The authors therefore suggest that impaired formation or function of the human decidua might allow DCs to leave the decidua to initiate an aggressive immune response toward the fetus, something that might contribute to poor pregnancy outcomes. In an accompanying commentary, Bali Pulendran, at Emory Vaccine Center at Yerkes National Primate Research Center, Atlanta, discusses how this new research affects current thinking about avoiding immune surveillance at the maternal/fetal interface. TITLE: Dendritic cell entrapment within the pregnant uterus inhibits immune surveillance of the maternal/fetal interface in mice AUTHOR CONTACT: Adrian Erlebacher New York University School of Medicine, New York, New York, USA. View the PDF of this article at: https://www.the-jci.org/article.php?id=38714 ACCOMPANYING COMMENTARY TITLE: Restraining order for dendritic cells: all quiet on the fetal front AUTHOR CONTACT: Bali Pulendran Emory Vaccine Center at Yerkes National Primate Research Center, Atlanta, Georgia, USA. View the PDF of this article at: https://www.the-jci.org/article.php?id=39946 Karen Honey Journal of Clinical Investigation


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